Dose
The following doses have been studied in scientific research, according to Natural Medicines:
Application on the skin:
A cream containing 50% DMSO was applied up to 5 times a day for 2 to 12 months to treat chronic pain caused by a condition called complex regional pain syndrome.
To prevent skin and tissue damage caused by intravenous fluid leakage in chemotherapeutic treatments, a bandage containing 77-90% DMSO solution was used, applied every 3 to 8 hours for 2 weeks.
Between 50 and 40% idoxuridine in DMSO was applied within 48 hours of the appearance of a rash caused by shingles (herpes zoster), and every 4 hours for the next few days until the skin began to heal.
Inside the bladder
DMSO is an FDA approved product for the treatment of interstitial cystitis. Healthcare providers drip a DMSO solution into the bladder through a tube called a catheter. Once the catheter is removed, the patient is asked to hold the solution for a moment before urinating. This procedure also applies to inflammatory bladder disease.
Concern about its use
DMSO is considered safe as long as it is used as a prescription drug. It is important not to use DMSO products that are not prescribed by a healthcare professional, as there is a concern that some of these are “industrial grade” and are therefore not accepted for human use.
In that case, they are not considered safe, because they may contain impurities that can have a harmful effect on health. To make matters worse, DMSO easily penetrates through the skin so these impurities are quickly absorbed by the body.
Some side effects of ingesting DMSO include skin reactions, headache, dizziness, drowsiness, breathing, vision, and blood problems, garlic-like taste, breath, and body odor, nausea, vomiting, diarrhea, and constipation.
There is not enough reliable information on whether it is safe to take DMSO during pregnancy or breastfeeding, so caution or avoid its use is advised. This warning also extends to people with diabetes, as it could alter the way insulin works, with blood disorders, as it could cause the breakdown of red blood cells, or with liver and kidney problems.