Cocarboxylase 4% Injectable 25mL Carzilasa®

What is carzylase?

Carzilase® is the registered trademark of a synthetic medicine that uses cocarboxylase (thiamine pyrophosphate) as its active ingredient, a chemical compound derived from thiamine which belongs to the line of medicines with nutritional properties, with an effect on the body’s energy metabolism

What is it used for?

Thanks to its mechanism of action, carzylase® acts as a coenzyme mainly in enzymatic reactions of oxidative decarboxylation of pyruvic acid, which in its next step allows the production of energy through the Krebs cycle and subsequent glycolysis in the cellular respiration process.

It has been used as a complementary treatment for:

• Thiamine pyrophosphate deficiency.
• The immediate reactivation of the Krebs cycle.
• Acute, general or regional ischemic processes.
• Cerebral or myocardial vascular accident.
• Renal or mesenteric thrombosis.
• In cases of anesthetic accidents, neonatal hypoxia.
• Diabetes mellitus, diabetic coma and shock of various etiologies.
• Revascularization of mortified tissues in patients with problems in microcirculation in blood vessels.
• Liver failure and cirrhosis, as an auxiliary medication.
• Metabolic and diabetic acidosis.
• Senile dementia and Alzheimer’s.
• Wernicke’s encephalopathy and metabolic alterations due to chronic alcoholism.
• Neuropathies in general.

Dosage and routes of administration of carzylase

The presentation of carzilase® is as an injectable solution in a vial, which contains 40 mg cocarboxylase, its administration depending on the case to be treated by intramuscular (I.M.) or oral route and the dosage as a reference, can be as explained below:

Injectable solution: 1 to 5 ml every 4 to 72 hours by I.M. is recommended. slow, up to 25 ml dissolved in 500 ml of isotonic sodium chloride or glucose solution for application of slow infusion, according to medical recommendation.

Avoid if you have:

History of hypersensitivity to thiamine pyrophosphate.